Language function and dysfunction lab
At the Language Function and Dysfunction Lab, we study the psychology, neuropsychology, and neurobiology of language in healthy individuals and in individuals with brain damage.
Our approach is bi-directional. On the one hand, we use models from cognitive neuroscience to better understand language function in neurological populations with the goal of contributing to the development of novel diagnostic tools and methods to improve language capacity in patients. On the other hand, we use observations of the breakdown of language and communicative abilities following brain insult to obtain unique insights informative for cognitive (neuro)science models.
We have a strong focus on language production (because, of course, you can’t do it all!), but are also interested in comprehension and, especially, the intersection between production and comprehension. Most of our work is based on behavioural measures, electrophysiology, diffusion-weighted imaging, and non-invasive brain stimulation.
We are also part of the Adaptive Language for Healthy Brain and Society.
Looking for an internship? Contact us!
Research line
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Research line
We will be again at SNL this year (from our homes). Follow the links for more. Matteo will present his work on semantic and phonological context effects using picture-word interference and EEG.
We are excited about participating in and presenting at the International Workshop on Language Production this year (from our homes). Follow the links for more (links will be updated soon).
We are excited about attending SNL this year (from our homes). Follow the links for more. Check Joanna’s poster for exciting findings on the temporal lobe white matter in humans vs chimps.
We are very excited to present at Science of Aphasia. Click on the links to see more. We will update the pages to include more info later. Joanna will give a talk on comparative neuroanatomy of the posterior temporal lobe at the white matter level: chimps vs humans!
We will be presenting lots of interesting stuff at SNL this year. Click on the links to see more. We will update the pages to include more info later.
Source reconstruction of magnetoencephalography (MEG) has been used to assess brain reorganization after brain damage, such as stroke. Lesions result in parts of the brain having an electrical conductivity that differs from the normal values. The effect this has on the forward solutions (i.e., the propagation of electric currents and …
The biological foundation for the language-ready brain in the human lineage remains a debated subject. In humans, the arcuate fasciculus (AF) white matter and the posterior portions of the middle temporal gyrus are crucial for language. Compared with other primates, the human AF has been shown to dramatically extend into the …
Background: Neurocognition and speech, relevant domains in head and neck cancer (HNC), may be affected pretreatment. However, the prevalence of pretreatment deficits and their possible concurrent predictors are poorly understood. Methods: Using an HNC prospective cohort (Netherlands Quality of Life and Biomedical Cohort Study, N ≥ …
Primary progressive aphasia (PPA) is a clinical neurodegenerative syndrome with word finding problems as a core clinical symptom. Many aspects of word finding have been clarified in psycholinguistics using picture naming and a picture-word interference (PWI) paradigm, which emulates naming under contextual noise. However, little is …
Studies suggest that alpha–beta power decreases index word retrieval in context-driven word production. We recorded the electroencephalogram from patients with stroke lesions encompassing the left lateral-temporal and inferior-parietal regions or left lateral-frontal lobe. Results indicate a critical role for the left posterior, but not frontal cortex, in generating the alpha–beta power decreases underlying context‐driven word production.
Language is typically studied in isolation from memory. We demonstrate that the same neuronal computations used by the hippocampus for memory also subserve online language usage. These findings represent a major step in integrating the studies of language and memory, significantly expanding the role of hippocampal theta oscillations.
Our understanding of post-stroke language function is largely based on older age groups, who show increasing age-related brain pathology and neural reorganisation. To illustrate language outcomes in the young-adult brain, we present the case of J., a 23 y.o. woman with chronic aphasia from a left-hemisphere stroke affecting the …
Background: For speakers with mild to moderate expressive aphasia the ultimate goal of aphasia therapy is to improve verbal functional communication, which may be assessed with the Amsterdam-Nijmegen Test for Everyday Language (ANELT; Blomert et al., 1995). The ANELT is based on a qualitative and transcription-less method of …
Since the second-half of the twentieth century, intracranial electroencephalography (iEEG), including both electrocorticography (ECoG) and stereo-electroencephalography (sEEG), has provided an intimate view into the human brain. At the interface between fundamental research and the clinic, iEEG provides both high temporal resolution …
Alpha and beta power decreases have been associated with prediction in a variety of cognitive domains. Recent studies in sentence comprehension have also reported alpha and/or beta power decreases preceding contextually predictable words, albeit with remarkable spatiotemporal variability across reports. To contribute to the …
In the present study, a modified replication of Schuhmann et al. (2012), we used chronometric TMS to probe the time-course of three brain regions during a picture naming task. The left inferior frontal gyrus (IFG), left posterior middle temporal gyrus (pMTG) and left posterior superior temporal gyrus (pSTG) were all separately …
