Language function and dysfunction lab
At the Language Function and Dysfunction Lab, we study the psychology, neuropsychology, and neurobiology of language in healthy individuals and in individuals with brain damage.
Our approach is bi-directional. On the one hand, we use models from cognitive neuroscience to better understand language function in neurological populations with the goal of contributing to the development of novel diagnostic tools and methods to improve language capacity in patients. On the other hand, we use observations of the breakdown of language and communicative abilities following brain insult to obtain unique insights informative for cognitive (neuro)science models.
We have a strong focus on language production (because, of course, you can’t do it all!), but are also interested in comprehension and, especially, the intersection between production and comprehension. Most of our work is based on behavioural measures, electrophysiology, diffusion-weighted imaging, and non-invasive brain stimulation.
For teaching resources on language production, check Speaking: The free book (chapter). It’s free and at an appropriate entry level!
Looking for an internship? Contact us!
Research line
File drawer
Research line
We will be again at SNL this year (from our homes). Follow the links for more. Matteo will present his work on semantic and phonological context effects using picture-word interference and EEG.
We are excited about participating in and presenting at the International Workshop on Language Production this year (from our homes). Follow the links for more (links will be updated soon).
We are excited about attending SNL this year (from our homes). Follow the links for more. Check Joanna’s poster for exciting findings on the temporal lobe white matter in humans vs chimps.
We are very excited to present at Science of Aphasia. Click on the links to see more. We will update the pages to include more info later. Joanna will give a talk on comparative neuroanatomy of the posterior temporal lobe at the white matter level: chimps vs humans!
We will be presenting lots of interesting stuff at SNL this year. Click on the links to see more. We will update the pages to include more info later.
Source reconstruction of magnetoencephalography (MEG) has been used to assess brain reorganization after brain damage, such as stroke. Lesions result in parts of the brain having an electrical conductivity that differs from the normal values. The effect this has on the forward solutions (i.e., the propagation of electric currents and …
The biological foundation for the language-ready brain in the human lineage remains a debated subject. In humans, the arcuate fasciculus (AF) white matter and the posterior portions of the middle temporal gyrus are crucial for language. Compared with other primates, the human AF has been shown to dramatically extend into the …
Background: Neurocognition and speech, relevant domains in head and neck cancer (HNC), may be affected pretreatment. However, the prevalence of pretreatment deficits and their possible concurrent predictors are poorly understood. Methods: Using an HNC prospective cohort (Netherlands Quality of Life and Biomedical Cohort Study, N ≥ …
Primary progressive aphasia (PPA) is a clinical neurodegenerative syndrome with word finding problems as a core clinical symptom. Many aspects of word finding have been clarified in psycholinguistics using picture naming and a picture-word interference (PWI) paradigm, which emulates naming under contextual noise. However, little is …
Studies suggest that alpha–beta power decreases index word retrieval in context-driven word production. We recorded the electroencephalogram from patients with stroke lesions encompassing the left lateral-temporal and inferior-parietal regions or left lateral-frontal lobe. Results indicate a critical role for the left posterior, but not frontal cortex, in generating the alpha–beta power decreases underlying context‐driven word production.
Language is typically studied in isolation from memory. We demonstrate that the same neuronal computations used by the hippocampus for memory also subserve online language usage. These findings represent a major step in integrating the studies of language and memory, significantly expanding the role of hippocampal theta oscillations.
Individuals in the preclinical stage of Alzheimer’s disease (amnestic mild cognitive impairment [aMCI] and mild dementia) primarily exhibit episodic memory deficits, while the presence of semantic control impairments remains understudied. To explore semantic control and white matter connectivity in individuals with aMCI and …
This book was written as a resource for teaching language production at the Bachelor’s and Master’s level or for initiating trainees on the topic more generally. Some basic knowledge of cognitive psychology and linguistics is assumed. These materials only exist thanks to the help of the authors of the different sections. Sections are …
Background: Discourse production is a fundamental aspect of everyday life. There is a growing body of research on discourse production in persons with aphasia (PWA) but one understudied aspect of discourse production is the use of discourse particles. Understanding the role of discourse particles in PWA is crucial given the recent …
Power decreases, or desynchronization, of sensorimotor alpha and beta oscillations (i.e., alpha and beta ERD) have long been considered as indices of sensorimotor control in overt speech production. However, their specific functional roles are not well understood. Hence, we first conducted a systematic review to investigate how these …
Language control in bilingual speakers is thought to be implicated in effectively switching between languages, inhibiting the non-intended language, and continuously monitoring what to say and what has been said. It has been a matter of controversy concerning whether language control operates in a comparable manner to cognitive …
