impairment

Corpus callosum involvement in language ability after left-hemispheric stroke

The left hemisphere (LH) is dominant for language in the majority of the healthy population. Patients with LH-damage may show global right-hemisphere (RH) activity for language. This makes interhemispheric transfer a good candidate for a brain …

Microstructural integrity of crucial white-matter tracts for category fluency in elderly with cerebral small vessel disease

Recent studies have suggested that language production abilities decline in patients with small vessel disease (SVD) a pathology that is one of the main contributors of cognitive impairment in older adults. The loss of microstructural integrity in …

How the speed of word finding depends on ventral tract integrity in primary progressive aphasia

Primary progressive aphasia (PPA) is a clinical neurodegenerative syndrome with word finding problems as a core clinical symptom. Many aspects of word finding have been clarified in psycholinguistics using picture naming and a picture-word …

Lexical-semantic and executive deficits revealed by computational modelling: a drift diffusion model perspective

Flexible language use requires coordinated functioning of two systems: conceptual representations and control. The interaction between two systems can be observed when people are asked to matcha word to a picture. Participants are slower and less …

Semi-spontaneous language production in Dutch speaking people with primary progressive aphasia

Primary progressive aphasia (PPA) is a neurodegenerative language disorder. Despite recent research, this disorder is studied less than vascular aphasia. There are three main accepted variants: nonfluent/agrammatic PPA (nfv-PPA), semantic PPA …

Language neuroplasticity in brain tumour patients revealed by magnetoencephalography

Language impairment in brain tumour patients may be missed since standardised tests fail to capture mild deficits. Neuroplasticity may also contribute to minimising language impairments. To address this possibility, we examined 14 patients with …

Cognitive and speech functioning in HNC: baseline prevalence and possible causes

__Background.__   The impact of treatment for head and neck cancer (HNC) on speech and cognitive functioning is well studied. Moreover, recent research has identified speech and cognitive deficits in HNC patients already prior to treatment, but …

Investigating the semantic control network and its structural decline in mild cognitive impairment and mild dementia

Although the episodic and semantic memory systems have long been studied separately, recent literature revealed shared neural substrates, including the medial temporal lobe (MTL). One important aspect of semantic memory is semantic control, which …

The role of the uncinate fasciculus and inferior longitudinal fasciculus in healthy and disordered language production

The role of ventral fiber pathways in healthy and disordered language production

While neuroimaging research on language production has traditionally focused primarily on grey matter, several recent studies highlight the involvement of ventral and dorsal white matter pathways. A debated issue concerns the exact functional role of …