impairment

Time-course of right-hemisphere recruitment during word production following left-hemisphere damage: A single case of young stroke

Our understanding of post-stroke language function is largely based on older age groups, who show increasing age-related brain pathology and neural reorganisation. To illustrate language outcomes in the young-adult brain, we present the case of J., a …

A transcription-less quantitative analysis of aphasic discourse elicited with an adapted version of the Amsterdam-Nijmegen Everyday Language Test (ANELT)

Background: For speakers with mild to moderate expressive aphasia the ultimate goal of aphasia therapy is to improve verbal functional communication, which may be assessed with the Amsterdam-Nijmegen Test for Everyday Language (ANELT; Blomert et al., …

Long-term cognitive, psychosocial, and neurovascular complications of unilateral head and neck irradiation in young to middle-aged adults

Background: With a growing, younger population of head and neck cancer survivors, attention to long-term side-effects of prior, often radiotherapeutic, treatment is warranted. Therefore, we studied the long-term cognitive effects in young adult …

Declarative Learning, Priming, and Procedural Learning Performances comparing Individuals with Amnestic Mild Cognitive Impairment, and Cognitively Unimpaired Older Adults

Objective: While declarative learning is dependent on the hippocampus, procedural learning and repetition priming can operate independently from the hippocampus, making them potential targets for behavioral interventions that utilize non-declarative …

The Diagnostic Value of Language Screening in Primary Progressive Aphasia: Validation and Application of the Sydney Language Battery

Purpose: The three variants of primary progressive aphasia (PPA) differ in clinical presentation, underlying brain pathology, and clinical course, which stresses the need for early differentiation. However, brief cognitive tests that validly …

Prevalence of neurocognitive and perceived speech deficits in patients with head and neck cancer before treatment: Associations with demographic, behavioral, and disease-related factors

Background: Neurocognition and speech, relevant domains in head and neck cancer (HNC), may be affected pretreatment. However, the prevalence of pretreatment deficits and their possible concurrent predictors are poorly understood. Methods: Using an …

Disentangling language production impairments in Parkinson’s Disease

Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by cardinal motor symptoms, including resting tremor, rigidity and bradykinesia, and cognitive impairments, such as deficits in executive function, attention and short-term …

Repetition priming in individuals with amnestic Mild Cognitive Impairment and Alzheimer’s dementia: A systematic review and meta-analysis.

The literature on repetition priming in Alzheimer’s disease (AD) is inconsistent, with some findings supporting spared priming while others do not. Several factors may explain these inconsistencies, including AD severity (e.g., dementia vs. Mild …

The effect of deep brain stimulation of the subthalamic nucleus on language function in Parkinson’s disease: A systematic review

Purpose: This systematic review focuses on the effect of bilateral Deep Brain Stimulation (DBS) of the Subthalamic Nucleus (STN) on language function in Parkinson’s Disease (PD). It fills an important gap in recent reviews, by considering other …

White matter hyperintensities at critical crossroads for executive function and verbal abilities in small vessel disease

The presence of white matter lesions in patients with cerebral small vessel disease (SVD) is among the main causes of cognitive decline. We investigated the relation between white matter hyperintensity (WMH) locations and executive and language …