Our understanding of post-stroke language function is largely based on older age groups, who show increasing age-related brain pathology and neural reorganisation. To illustrate language outcomes in the young-adult brain, we present the case of J., a …
The biological foundation for the language-ready brain in the human lineage remains a debated subject. In humans, the arcuate fasciculus (AF) white matter and the posterior portions of the middle temporal gyrus are crucial for language. Compared with …
The presence of white matter lesions in patients with cerebral small vessel disease (SVD) is among the main causes of cognitive decline. We investigated the relation between white matter hyperintensity (WMH) locations and executive and language …
The left hemisphere (LH) is dominant for language in the majority of the healthy population. Patients with LH-damage may show global right-hemisphere (RH) activity for language. This makes interhemispheric transfer a good candidate for a brain …
Recent studies have suggested that language production abilities decline in patients with small vessel disease (SVD) a pathology that is one of the main contributors of cognitive impairment in older adults. The loss of microstructural integrity in …
Primary progressive aphasia (PPA) is a clinical neurodegenerative syndrome with word finding problems as a core clinical symptom. Many aspects of word finding have been clarified in psycholinguistics using picture naming and a picture-word …
The left temporal lobe is claimed to be involved in language comprehension in both the classical (Wernicke, 1874) and contemporary dual-pathway models for language processing (Hickok & Poeppel, 2007, Roelofs, 2014), but the role of neuroanatomical …
Although the episodic and semantic memory systems have long been studied separately, recent literature revealed shared neural substrates, including the medial temporal lobe (MTL). One important aspect of semantic memory is semantic control, which …
The frontal aslant tract (FAT) is a white matter structure joining the anterior supplementary and pre-supplementary motor area (SMA and pre-SMA) to the inferior and middle frontal gyri. FAT shows leftward asymmetry (Catani et al., 2012), which …