impairment

The Diagnostic Value of Language Screening in Primary Progressive Aphasia: Validation and Application of the Sydney Language Battery

Purpose: The three variants of primary progressive aphasia (PPA) differ in clinical presentation, underlying brain pathology, and clinical course, which stresses the need for early differentiation. However, brief cognitive tests that validly …

Prevalence of neurocognitive and perceived speech deficits in patients with head and neck cancer before treatment: Associations with demographic, behavioral, and disease-related factors

Background: Neurocognition and speech, relevant domains in head and neck cancer (HNC), may be affected pretreatment. However, the prevalence of pretreatment deficits and their possible concurrent predictors are poorly understood. Methods: Using an …

Disentangling language production impairments in Parkinson’s Disease

Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by cardinal motor symptoms, including resting tremor, rigidity and bradykinesia, and cognitive impairments, such as deficits in executive function, attention and short-term …

Repetition priming in individuals with amnestic Mild Cognitive Impairment and Alzheimer’s dementia: A systematic review and meta-analysis.

The literature on repetition priming in Alzheimer’s disease (AD) is inconsistent, with some findings supporting spared priming while others do not. Several factors may explain these inconsistencies, including AD severity (e.g., dementia vs. Mild …

The effect of deep brain stimulation of the subthalamic nucleus on language function in Parkinson’s disease: A systematic review

Purpose: This systematic review focuses on the effect of bilateral Deep Brain Stimulation (DBS) of the Subthalamic Nucleus (STN) on language function in Parkinson’s Disease (PD). It fills an important gap in recent reviews, by considering other …

White matter hyperintensities at critical crossroads for executive function and verbal abilities in small vessel disease

The presence of white matter lesions in patients with cerebral small vessel disease (SVD) is among the main causes of cognitive decline. We investigated the relation between white matter hyperintensity (WMH) locations and executive and language …

Corpus callosum involvement in language ability after left-hemispheric stroke

The left hemisphere (LH) is dominant for language in the majority of the healthy population. Patients with LH-damage may show global right-hemisphere (RH) activity for language. This makes interhemispheric transfer a good candidate for a brain …

Microstructural integrity of crucial white-matter tracts for category fluency in elderly with cerebral small vessel disease

Recent studies have suggested that language production abilities decline in patients with small vessel disease (SVD) a pathology that is one of the main contributors of cognitive impairment in older adults. The loss of microstructural integrity in …

How the speed of word finding depends on ventral tract integrity in primary progressive aphasia

Primary progressive aphasia (PPA) is a clinical neurodegenerative syndrome with word finding problems as a core clinical symptom. Many aspects of word finding have been clarified in psycholinguistics using picture naming and a picture-word …

Lexical-semantic and executive deficits revealed by computational modelling: a drift diffusion model perspective

Flexible language use requires coordinated functioning of two systems: conceptual representations and control. The interaction between two systems can be observed when people are asked to matcha word to a picture. Participants are slower and less …