aphasia

Exploring the production of discourse particles by persons with aphasia

Background: Discourse production is a fundamental aspect of everyday life. There is a growing body of research on discourse production in persons with aphasia (PWA) but one understudied aspect of discourse production is the use of discourse …

Cognitive impairment after a stroke in young adults: a systematic review and meta-analysis

Background: Information about cognitive functioning is vital in the management of stroke, but the literature is mostly based on data from individuals older than 50 years of age who make up the majority of the stroke population. As cognitive …

Brain areas critical for naming: a systematic review and meta-analysis of lesion-symptom mapping studies

Lesion-symptom mapping (LSM) studies have revealed brain areas critical for naming, typically finding significant associations between damage to left temporal, inferior parietal and inferior fontal regions and impoverished naming performance. …

Time-course of right-hemisphere recruitment during word production following left-hemisphere damage: A single case of young stroke

Our understanding of post-stroke language function is largely based on older age groups, who show increasing age-related brain pathology and neural reorganisation. To illustrate language outcomes in the young-adult brain, we present the case of J., a …

The Diagnostic Value of Language Screening in Primary Progressive Aphasia: Validation and Application of the Sydney Language Battery

Purpose: The three variants of primary progressive aphasia (PPA) differ in clinical presentation, underlying brain pathology, and clinical course, which stresses the need for early differentiation. However, brief cognitive tests that validly …

How the speed of word finding depends on ventral tract integrity in primary progressive aphasia

Primary progressive aphasia (PPA) is a clinical neurodegenerative syndrome with word finding problems as a core clinical symptom. Many aspects of word finding have been clarified in psycholinguistics using picture naming and a picture-word …

Lexical selection with competing distractors: Evidence from left temporal lobe lesions

According to the competition account of lexical selection in word production, conceptually driven word retrieval involves the activation of a set of candidate words in left temporal cortex and competitive selection of the intended word from this set, …

Voxel-based lesion analysis of brain regions underlying reading and writing

The neural basis of reading and writing has been a source of inquiry as well as controversy in the neuroscience literature. Reading has been associated with both left posterior ventral temporal zones (termed the "visual word form area") as well as …

Lesion evidence for a critical role of left posterior but not frontal areas in alpha-beta power decreases during context-driven word production

Studies suggest that alpha–beta power decreases index word retrieval in context-driven word production. We recorded the electroencephalogram from patients with stroke lesions encompassing the left lateral-temporal and inferior-parietal regions or left lateral-frontal lobe. Results indicate a critical role for the left posterior, but not frontal cortex, in generating the alpha–beta power decreases underlying context‐driven word production.

Neuroplasticity of language in left-hemisphere stroke: evidence linking subsecond electrophysiology and structural connections

Our understanding of neuroplasticity following stroke is predominantly based on neuroimaging measures that cannot address the subsecond neurodynamics of impaired language processing. We combined behavioral and electrophysiological measures and …