stroke

Exploring the production of discourse particles by persons with aphasia

Background: Discourse production is a fundamental aspect of everyday life. There is a growing body of research on discourse production in persons with aphasia (PWA) but one understudied aspect of discourse production is the use of discourse …

The impact of CSF-filled cavities on scalp EEG and its implications

Previous studies have found EEG amplitude and scalp topography differences between neurotypical and neurological/neurosurgical groups, being interpreted at the cognitive level. However, these comparisons are invariably accompanied by anatomical …

Cognitive impairment after a stroke in young adults: a systematic review and meta-analysis

Background: Information about cognitive functioning is vital in the management of stroke, but the literature is mostly based on data from individuals older than 50 years of age who make up the majority of the stroke population. As cognitive …

Brain areas critical for naming: a systematic review and meta-analysis of lesion-symptom mapping studies

Lesion-symptom mapping (LSM) studies have revealed brain areas critical for naming, typically finding significant associations between damage to left temporal, inferior parietal and inferior fontal regions and impoverished naming performance. …

Systematic review and meta-analyses of word production abilities in dysfunction of the basal ganglia: Stroke, small vessel disease, Parkinson's disease, and Huntington's disease

Clinical populations with basal ganglia pathologies may present with language production impairments, which are often described in combination with comprehension measures or attributed to motor, memory, or processing-speed problems. In this …

Time-course of right-hemisphere recruitment during word production following left-hemisphere damage: A single case of young stroke

Our understanding of post-stroke language function is largely based on older age groups, who show increasing age-related brain pathology and neural reorganisation. To illustrate language outcomes in the young-adult brain, we present the case of J., a …

A transcription-less quantitative analysis of aphasic discourse elicited with an adapted version of the Amsterdam-Nijmegen Everyday Language Test (ANELT)

Background: For speakers with mild to moderate expressive aphasia the ultimate goal of aphasia therapy is to improve verbal functional communication, which may be assessed with the Amsterdam-Nijmegen Test for Everyday Language (ANELT; Blomert et al., …

Estimating the influence of stroke lesions on MEG source reconstruction

Source reconstruction of magnetoencephalography (MEG) has been used to assess brain reorganization after brain damage, such as stroke. Lesions result in parts of the brain having an electrical conductivity that differs from the normal values. The …

Corpus callosum involvement in language ability after left-hemispheric stroke

The left hemisphere (LH) is dominant for language in the majority of the healthy population. Patients with LH-damage may show global right-hemisphere (RH) activity for language. This makes interhemispheric transfer a good candidate for a brain …

Lexical-semantic and executive deficits revealed by computational modelling: a drift diffusion model perspective

Flexible language use requires coordinated functioning of two systems: conceptual representations and control. The interaction between two systems can be observed when people are asked to matcha word to a picture. Participants are slower and less …